U.S. intelligence officer Amanda Waller has assembled a team of the world's most dangerous, incarcerated super villains, provides them with the most powerful arsenal at the government's disposal, and sends them off on a mission to defeat an enigmatic, powerful entity. But once they realize they weren't picked to succeed but chosen for their patent culpability when they inevitably fail, will the Suicide Squad resolve to die trying, or decide it's every man for himself?